Description

Abriva Plus Tablet 400/100mg –(Sofosbuvir & Velpatasvir) Hepatitis C Treatment

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Are you looking for an effective, all-in-one treatment for Chronic Hepatitis C? Abriva Plus Tablet (Sofosbuvir 400mg / Velpatasvir 100mg) is a breakthrough direct-acting antiviral (DAA) medication designed to eliminate the Hepatitis C virus (HCV) from the body. Manufactured by the renowned CCL Pharma, Abriva Plus offers a high cure rate for patients across all genotypes of the virus.

What is Abriva Plus Tablet?

Abriva Plus is a fixed-dose combination of two powerful antiviral ingredients:

  1. Sofosbuvir (400mg): A nucleotide analog polymerase inhibitor.
  2. Velpatasvir (100mg): An NS5A inhibitor.

Together, these components block the enzymes the virus needs to replicate, eventually clearing the infection from the bloodstream. Unlike older treatments, Abriva Plus is “pangenotypic,” meaning it works against all six major genotypes (1-6) of Hepatitis C.


Key Uses & Benefits of Abriva Plus

Abriva Plus is primarily prescribed for the treatment of Chronic Hepatitis C Virus (HCV) infection in adults and pediatric patients (6 years and older).

  • Pangenotypic Coverage: Effective against genotypes 1, 2, 3, 4, 5, and 6.
  • High Success Rate: Clinical trials show a cure rate (SVR12) of over 95-98%.
  • Simplified Regimen: One pill a day eliminates the need for complex multi-drug schedules.
  • Cirrhosis Management: Safe for use in patients with compensated cirrhosis and, when combined with Ribavirin, for those with decompensated cirrhosis.

Abriva Plus Tablet Dosage and Administration

Strict adherence to the prescribed dosage is vital for the successful clearance of the virus.

  • Standard Dosage: One tablet daily, taken orally.
  • With or Without Food: You can take Abriva Plus with or without a meal. However, taking it at the same time every day helps maintain a consistent level of medicine in your system.
  • Duration: The standard treatment duration is typically 12 weeks. Your doctor may adjust this based on your liver condition (cirrhosis status) or previous treatment history.
  • Missed Dose: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed one. Do not double the dose.

Side Effects of Abriva Plus

While Abriva Plus is generally well-tolerated, some patients may experience mild side effects as the body adjusts to the medication.

Common Side Effects:
  • Headache
  • Fatigue (Tiredness)
  • Nausea
  • Insomnia (Difficulty sleeping)
  • Mild diarrhea
Rare but Serious Side Effects:
  • Bradycardia (Slow Heart Rate): Particularly if taken with the heart medication Amiodarone.
  • Allergic Reactions: Rash, swelling of the face, or difficulty breathing.
  • Hepatitis B Reactivation: If you have previously had Hepatitis B, it may become active again. Your doctor will test you for HBV before starting Abriva Plus.

Precautions and Warnings

Before starting your Abriva Plus 12-week course, consult your physician regarding the following:

  • Drug Interactions: Inform your doctor if you are taking antacids, H2 blockers, or Proton Pump Inhibitors (PPIs), as they can reduce the absorption of Velpatasvir.
  • Pregnancy/Breastfeeding: Consult a specialist. While Sofosbuvir/Velpatasvir data is limited, it is often avoided unless necessary.
  • Kidney & Liver Health: Ensure your doctor has your latest LFTs (Liver Function Tests) and Renal reports.

Abriva Plus Tablet Price in Pakistan

Finding high-quality healthcare at a reasonable cost is essential. Current Price at Ravi Medical Store: Rs. 9000 per pack.

At this price point, Abriva Plus provides a cost-effective alternative to international brands while maintaining global manufacturing standards by CCL Pharma.


Why Buy Abriva Plus Tablet from Us?
  • 100% Authentic: We source directly from authorized distributors.
  • Proper Storage: Medicines are kept in temperature-controlled environments to maintain efficacy.
  • Fast Delivery: Reliable shipping across Pakistan.
  • Expert Support: Our pharmacists are available to answer your queries.

It is strongly advised to avoid alcohol during Hepatitis C treatment, as alcohol causes further liver damage and can hinder the healing process.


Disclaimer: This information is for educational purposes only. Always consult a certified hepatologist or gastroenterologist before starting any medication.